Mun na sisi jiri bɛ wele ko ‘nature’s anti-inflammatory powerhouse’?

Sisi jiri bɔlenw kɛnɛyali gundo .

Sisi jiri bɔlen (kotini coggygria) bɛ bɔ nin Mediterane kɔgɔji buluw ni a buluw la-Natif jiri la ka tɛmɛ CO2 bɔli ɲɛtaa fɛ. Bi ɲininiw y’a jira k’a ka fɛnɲɛnamafagalanw ni fɛnɲɛnamafagalanw ɲagaminen ɲɔgɔn na, minnu b’a kɛ fura barikama ye funu ni oksidan degun na.

Core active components and mechanisms .

Fisetin (a bɛ se ka kɛ flavonoid antioxydant ye) .

Anti-Fɛnɲɛnɛma wale .: a bɛ NF-κB taamasiɲɛ sira bali, ka Pro-Fɛnɲɛnɛma sitokiniw (TNF- , IL-6) dɔgɔya fo ka se 50% ma

Neuroprotective Effects .: A bɛ joli tɛmɛ-Baro barika la walasa ka NRF2 sira baara, ka glutathione hakɛ bonya senfagabana na ni 40% ye .

Senescence lakanani .: A bɛ mɔgɔkɔrɔbaw ka seliw jɛya (a jiralen don ka si hakɛ dɔgɔya-Marali minnu bɛ tali kɛ ɲɔgɔn na ni 35% ye baganw ka kalanw na)

Gallotanninw (polifenɔli kɛrɛnkɛrɛnnenw) .

Modulation microbiome .: A bɛ nafa sɔrɔ Akkermansia muciniphila (3-5 siɲɛ hakɛ caya) la ka sɔrɔ ka banakisɛw bali .

Farikolo lakanani .: A bɛ dɔ fara kolajɛni sɔrɔli kan ni fibɔrɔsi baara lawulili ye (kɛnɛyako sɛgɛsɛgɛliw y’a jira ko 25% bɛ kɛ kurukuruw la) .

Metabolic dɛmɛ .: A bɛ inisɔndiya sabati AMPK baarakɛli fɛ (glucose dɔgɔyali teliya la 15-20%)

Tumu nafamaw (Terpene complexe) .

ninakili nafa .: A bɛ kɛ i n’a fɔ fɛnɲɛnamafagalanw (FEV1 ɲɛtaa 12-15% Ɲɛgɛnɛsiraw banabagatɔw la) .

dimi mada .: A bɛ TRPV1 sɔrɔyɔrɔw sɛmɛntiya dimimadafura nɔw na (a bɛ tali kɛ lidokɛni 5% la dimi hakɛ sɛgɛsɛgɛliw la)

Banakisɛfagalanw ka baara .: A bɛ se ka kɛ fura ye- Staphylococcus suguya minnu bɛ se ka bana sɔrɔ (MIC 32-64 UG/ML) .

furakɛlicogo saba minnu bɛ se ka tiɲɛ kɛnɛyaso la .

1. Banakisɛfagalanw tali basigilen .

45% dɔgɔyali CRP hakɛ la (dɔgɔkun 12 sɛgɛsɛgɛli ni jolidɛsɛbanatɔw ye) .

Fɛɛrɛ caman bɛ sɔrɔ IBD taamasiɲɛw la (70% yafa hakɛ nɔgɔman-Kɔrɔsitɔw ka kirinni hakɛlama) .

2. Fari kɛnɛya ni anti-

A bɛ dɔ fara fari lamagacogo kan ni 28% ye (kɔriniyɔmu sumanikɛcogo) .

A bɛ dɔ bɔ UV-Pigimentation induite ni 40% (vs. placebo) ye .

3. Syndrome de metabolic (banakisɛfagalanw ka bana) .

A bɛ HBA1C jigin ni 0,8-1,2% ye sukarodunbana na sani a ka kɛ .

A bɛ dɔ bɔ kɔnɔbara fasaw dalajɛli la ni 15% ye (CT scan vertified) .

Baarakɛcogo sariyaw ka kɛɲɛ ni kɛnɛyako kuntilenna ye .

A tali ɲuman .

ka ɲɛsin sigida nɔfɛkow ma .: Aw bɛ dumuni nafamaw ta ni omega-3 ye walasa ka ɲɛnamaya sɔrɔcogo ɲɛ .

Baara kɛ ni a ye yɔrɔ min na .: 2-5% hakɛ serumw na fototalan kama .

Sinsinnanw faralen ɲɔgɔn kan .: A bɛ baara kɛ kosɛbɛ ni kurɔkumuni ye (1:1 ratio) .

Profil de safe .

▲ A bɛ se ka joli fanga bonya-Fura minnu bɛ kɛ ni INR ye ni warfarin bɛ a la)
▲ Bana minnu bɛ sɔrɔ fari la, olu man teli ka sɔrɔ ni u tali ye u la (Patch Test recommended) .
▲ Toxicité kɔlɔsilen tɛ a tata hakɛ la fo ka se 1g/kg ma baganw ka sɛgɛsɛgɛliw la .

Jogoɲumanya sɛgɛsɛgɛli .

1 HPLC-Fisetini hakɛ dantigɛlenw (a ka dɔgɔn 8%) .
2 Wild-A tigɛra ka bɔ Mediterane maraw la .
3 Nɛgɛ gɛlɛnw tɛ yen (ICP-MS seereyaw) .

Baarakɛlaw ka sɔrɔw sɛbɛnnenw .

"Ne ka sɔgɔsɔgɔninjɛ dimi dɔgɔyara fo ka se ka biologiki hakɛ dɔgɔya ni tila ye" - 54F, kalo 6 baara .
"Kolo 3 kɔfɛ, n farikolodɔgɔtɔrɔ ko n ka tile yɔrɔw tun bɛ i ko san 10 ka dɔgɔ" - 41M

Dalilu minnu bɛ sɔrɔ masinw fɛ .

NF-κB balili .(Tilebin fɛ blot sɛgɛsɛgɛli)

72,3% dɔgɔyali p65 nukiliya jiginni na .

Gut microbiome shifts .(16s rRNA sequencing) .

4,2-foli ka caya faacalibacterium prausnitzII .

Mun na aw bɛ sisiji bɔ?
Nin jiriforoko min tɛ jate kosɛbɛ, o bɛ nafa caman di ka bɔ joli lakanani na ka se farikoloɲɛnajɛ dɛmɛni ma, o bɛɛ bɛ kɛ ni fɛɛrɛw ye minnu bɛ tiɲɛ dɔnniya siratigɛ la. A tɛ i n’a fɔ furakɛli kelen-A ka phytocomplex suguya caman bɛ baara kɛ sira caman fɛ walasa ka farikolo balansi segin.